The v-atpase: small cargo large effects

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WebThe V-ATPase: small cargo, large effects. 来自 Elsevier 喜欢 0 阅读量： 104 作者： Karin Schumacher ， Melanie Krebs 摘要： About 30 years ago seminal reports of anion-sensitive proton-pumping activity associated with microsomal membranes initiated research on the plant vacuolar-type H +-ATPase (V-ATPase, VHA). WebMar 14, 2012 · VHA-c has a major role in transporting ions. In addition, it is involved in many stress responses such as salt stress, low temperature, heat and so on. The enhancement in the expression of V-H + -ATPase subunits has been demonstrated under salt- and abscisic acid (ABA)-induced stress (Kasai et al. 1994 ).

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Webtion of the proteolipid ring relative to subunit a of the V 0 domain. Subunit a is a 100 kDa transmembrane protein containing an NH 2-terminal cytoplasmic domain and a E G A ATP ADP + Pi E D F d V 1 V 0 E G B G H NT α NT α CT H CT C In H+ H+ Out e c,c” FIGURE 1. Structure and mechanism of the V-ATPase. The V-ATPase is composed of a ... WebThe large selection of styles and sizes includes small cargo trailers that are ideal for carrying tools and equipment around the yard or farm. You will also see cargo trailers that … malta food tour

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WebThe V-ATPase: small cargo, large effects. About 30 years ago seminal reports of anion-sensitive proton-pumping activity associated with microsomal membranes initiated … WebConsolidated freight is typically the cheapest way to ship heavy packages. Compare shipping rates for heavy items using the most common shipping methods: USPS. Parcel … WebV-ATPase: small cargo, large effects [2010] Schumacher, Karin; Krebs, Melanie; Access the full text Link; Link; Lookup at Google Scholar ... malta football team results

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WebSep 1, 2011 · Our recent iTRAQ analysis revealed that the levels of V-ATPase subunits A, C and E1 were significantly decreased in the presence of excess zinc in WT plants. 9 … WebOct 25, 2024 · The main functions of V-ATPase are to transport protons to vacuoles by ATP hydrolysis and to generate pH and potential energy gradients inside and outside vacuoles … malta football team playersWebFind the best used Vans near you. Every used car for sale comes with a free CARFAX Report. We have 12,744 Vans for sale that are reported accident free, 11,495 1-Owner cars, and … malta football players

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The v-atpase: small cargo large effects

V-ATPase: a potential pH sensor Nature Cell Biology

WebDec 23, 2012 · Strikingly, knocking down V-ATPase caused the cells to accumulate large and irregular CCPs with average neck diameters of 220 nm (compared with 97 nm in control cells), whereas constricted pits ... WebThe V-ATPase: small cargo, large effects. Author: Schumacher, Karin, Krebs, Melanie. Source: Current opinion in plant biology 2010 v.13 no.6pp. 724-730. ISSN: 1369-5266. …

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WebSep 1, 2011 · The plant V-ATPase, together with H + -pyrophosphatase (V-PPase), plays a central role in vacuole acidification, energizing the active transport of ions across the tonoplast and coordinately regulating turgor pressure and cell elongation. 1, 2 On the other hand, as a strategy to avoid the toxicity of several ions, plant cells take advantage of … WebDec 1, 2010 · The V-ATPase: Small cargo, large effects Authors: Karin Schumacher Universität Heidelberg Melanie Krebs Universität Heidelberg Request full-text Abstract …

WebThe v-ATPase is homologous to the F-type mitochondrial ATP synthase and these two enzyme complexes are thought to share genetic ancestors (Nelson, 1992). The v-ATPase uses energy from ATP hydrolysis to actively transport H + ions into the lysosome, thereby making the lumen more acidic. At least 13 different protein subunits form the complete v ... WebJan 1, 2024 · V-ATPases are ATP-driven proton pumps present in both intracellular and cell surface membranes of eukaryotes that function in many normal and disease processes. V …

Weba late endosome or lysosome to degrade its cargo. The opposing effects of two lysosomal inhibitors, chloroquine (CQ) and bafilomycin A 1 (BafA1), ... V-ATPase inhibitors impairs LC3A conjugation to the phago-some, which indicates the necessity of ROS and the V-ATPase in this process. Meanwhile, the researchers noticed that the WebApr 9, 2024 · In fact, 15 V-ATPase genes have mir-1 binding sites in their 3′ UTRs, and it is likely that mir-1-mediated regulation of these subunits is the cause of the muscle defects observed in mir-1 mutants. The V-ATPase complex requires specific concentrations of each of its subunits to properly form; thus, it is plausible that mir-1 is responsible ...

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WebWe also find that actin is required for sufficient entry of IFT material into flagella during assembly. These same effects are recapitulated with a myosin inhibitor, suggesting that actin may act via myosin in a pathway by which flagellar assembly is regulated by flagellar length. Many UC-authored scholarly publications are freely available on ... malta football twitterWebApr 20, 2012 · They found that removing the V 1 section of the V-ATPase using SCN − completely inhibited proton transport activity of the V-ATPase but did not affect the fusion reactions. By contrast, adding DCCD, an inhibitor that bound to the V 0 subunit Vma3, blocked vacuole fusion. malta football teamWebMay 25, 2024 · Yeast vacuoles are acidified by the V-ATPase, a protein complex comprised of the membrane embedded VO complex and the soluble cytoplasmic V1 complex. The assembly of the V1-VO holoenzyme is required for the transfer of H+ into the vacuole lumen for acidification. The assembly of the V1-VO holoenzyme is stabilized by the lipid … malta football ticketsWebMay 1, 2024 · cellular processes in all eukaryotes. Difficulty in obtaining preparations of purified V-ATPase from plants in sufficient quantities for structural analysis has hindered determining the 3D structure of the plant V-ATPase. We used the Legionella pneumophila effector SidK to affinity-purify the endogenous V-ATPase from lemon fruit. malta forecast weatherWebBafilomycin is a specific inhibitor of V-ATPase. To characterize the roll of the V-ATPase in viral replication we generated a Bafilomycin A1(BAF) resistant mutant of Sindbis virus (BRSV). malta forecast 14 daysWebSchumacher, K., & Krebs, M. (2010). The V-ATPase: small cargo, large effects. Current Opinion in Plant Biology, 13 (6), 724–730. doi:10.1016/j.pbi.2010.07.003 … malta forecast next 10 daysWebThe V-ATPase has a dual role in membrane transport and vesicle trafficking. The V-ATPase in the TGN/EE is essential. Endocytic and secretory trafficking require V-ATPase activity. … malta football stadium