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WebCollege of Pharmacy » University of Florida WebA closed system drug transfer device or " CSTD " is a drug transfer device that mechanically prohibits the transfer of environmental contaminants into a system and the escape of hazardous drug or vapor concentrations outside the system. Open versus closed systems are commonly applied in medical devices to maintain the sterility of a fluid … Weba drug using a vial adapter, CSTD syringe adapter and administration set with a Y-site and CSTD port. Task 3 – Liquid Compounding: Simulate admixing an IVPB medication using a vial adapter, CSTD syringe adapter and bag spike. This task is not outlined in the NIOSH protocol, however, was added to simulate a commonly performed task in the pharmacy. irs e postcard 2020