WebMar 25, 2024 · Here, we report that RRS1 is associated with cisplatin resistance in breast cancer cells. RRS1 silencing increased the sensitivity of MCF-7/DDP cells to cisplatin and inhibited cancer cell proliferation by blocking cell cycle distribution and enhancing apoptosis. AEG-1 (astrocyte elevated gene-1) promotes drug resistance by interfering with the ... WebThe platinum analogues, cisplatin and carboplatin, are among the most widely used chemotherapeutic agents in oncology. Both agents have a broad spectrum of clinical activity in numerous malignancies including gynaecological cancers, germ cell tumours, head and neck cancer, thoracic cancers and bladder cancer.
Shortage on 4 cancer drugs creates dire scenarios for patients
WebTreatment of lung cancer, the most common type of carcinoma, is difficult due to disease progression at the time of diagnosis, causing a high mortality rate. 1, 32 Cisplatin (DDP), also known as cis-diaminodichloplatin, is a powerful nonspecific drug blocking the cell cycle. 33, 34 DDP can enter cells through the passive transport. WebPemetrexed and cisplatin. Pemetrexed and cisplatin is a combination of two chemotherapy drugs. Pemetrexed is also called Alimta. You might have it as a treatment for non small … react themes \u0026 templates material-ui store
Randomized Phase III Evaluation of Cisplatin Plus Fluorouracil …
WebSquamous-cell carcinoma of the head and neck accounts for 5% of newly diagnosed cancers in adults in the United States and 8% of cancers worldwide. 1 The disease is potentially curable at an early... WebSep 3, 1991 · Concurrent cisplatin, infusional fluorouracil, and conventionally fractionated radiation therapy in head and neck cancer: dose-limiting mucosal toxicity WebApr 22, 2024 · Cancer cells repeatedly challenge researchers with their ability to develop resistance to treatments that were effective to begin with. Resistance to cisplatin, a … react themes bootstrap